Enantioselective total synthesis of (+)-amabiline.
نویسندگان
چکیده
The first total synthesis of (+)-amabiline, an unsaturated pyrrolizidine alkaloid from Cynoglossum amabile, is reported. This convergent, enantioselective synthesis proceeds in 15 steps (10-step longest linear sequence) in 6.2% overall yield and features novel methodology to construct the unsaturated pyrrolizidine or (-)-supinidine core.
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ورودعنوان ژورنال:
- Organic letters
دوره 14 7 شماره
صفحات -
تاریخ انتشار 2012